Our understanding of cannabinoids and how they relate not only to homeostasis The list of CBD oil benefits and health concerns treatable by CBD is so long. CBD oil benefits range from mental to physical and include relief from stress and anxiety, reduced symptoms of chronic conditions, and more!. It is increasingly becoming a health issue, and there are many positive reasons. CBD Central takes you through 11 amazing benefits of using CBD for chronic.
Benefits Health 11 Ways Your Oil CBD
CBD on its own was shown in to lower the incidence of diabetes in lab rats,[ ] and in an Israeli-American biopharmaceutical collective began stage 2 trials related to using CBD to treat diabetes. Respondents who had used cannabis in their lifetime but were not current users showed similar but less pronounced associations, indicating that the protective effect of cannabis fades with time. The research emerging about the interplay between cannabinoids and insulin regulation may lead to some major breakthroughs in the prevention of obesity and type 2 diabetes.
A study that measured data from 4, participants on the effect of cannabis on metabolic systems compared non-users to current and former users. Linked to diet and lifestyle, atherosclerosis is common in developed Western nations and can lead to heart disease or stroke. It is a chronic inflammatory disorder involving the progressive depositing of atherosclerotic plaques immune cells carrying oxidized LDL or low-density lipoproteins.
A growing body of evidence suggests that endocannabinoid signaling plays a critical role in the pathology of atherogenesis. Studies have demonstrated that inflammatory molecules stimulate the cycle leading to atherosclerotic lesions. The CB2 receptor is also stimulated by plant-based cannabinoids.
Reduced Risk of Cancer Could cannabidiol help prevent tumors and other cancers before they grow? A study showed that animals treated with CBD were significantly less likely to develop colon cancer after being induced with carcinogens in a laboratory. Continuing research is focused on the best ratio of CBD to THC and the most effective dose level in cancer prevention and treatment.
Cannabinoids are neuroprotective, meaning that they help maintain and regulate brain health. The effects appear to be related to several actions they have on the brain, including the removal of damaged cells and the improved efficiency of mitochondria. Extra glutamate, which stimulates nerve cells in the brain to fire, causes cells to become over-stimulated, ultimately leading to cell damage or death.
Thus, cannabinoids help protect brain cells from damage, keeping the organ healthy and functioning properly. CBD has also been shown to have an anti-inflammatory effect on the brain. As the brain ages, the creation of new neurons slows down significantly. In order to maintain brain health and prevent degenerative diseases, new cells need to be continuously created.
A study showed that low doses of CBD- and THC-like cannabinoids encouraged the creation of new nerve cells in animal models, even in aging brains. Cannabinoids are facilitative of the process of bone metabolism—the cycle in which old bone material is replaced by new at a rate of about 10 percent per year, crucial to maintaining strong, healthy bones over time.
CBD in particular has been shown to block an enzyme that destroys bone-building compounds in the body, reducing the risk of age-related bone diseases like osteoporosis and osteoarthritis.
In both of those diseases, the body is no longer creating new bone and cartilage cells. CBD helps spur the process of new bone-cell formation, which is why it has been found to speed the healing of broken bones and, due to a stronger fracture callus, decrease the likelihood of re-fracturing the bone bones are 35—50 percent stronger than those of non-treated subjects.
Protects and Heals the Skin The skin has the highest amount and concentration of CB2 receptors in the body. When applied topically as an infused lotion, serum, oil, or salve, the antioxidant a more powerful antioxidant than vitamins E and C  in CBD oil has many benefits and can repair damage from free radicals like UV rays and environmental pollutants. Cannabinoid receptors can be found in the skin and seem to be connected to the regulation of oil production in the sebaceous glands.
In fact, historical documents show that cannabis preparations have been used for wound healing in both animals and people in a range of cultures spanning the globe and going back thousands of years. The use of concentrated cannabis and CBD oils to benefit and treat skin cancer is gaining popularity with a number of well-documented cases of people curing both melanoma and carcinoma-type skin cancers with the topical application of CBD and THC products. Best known is the case of Rick Simpson, who cured his basal cell carcinoma with cannabis oil and now has a widely distributed line of products.
Cannabis applied topically is not psychoactive. Cannabinoids have been proven to have an anti-inflammatory effect in numerous studies. CBD engages with the endocannabinoid system in many organs throughout the body, helping to reduce inflammation systemically. The therapeutic potential is impressively wide-ranging, as inflammation is involved in a broad spectrum of diseases.
The oral use of cannabis and CBD for anxiety appears in a Vedic text dated around BCE, and it is one of the most common uses of the plant across various cultures. While THC can increase anxiety in some patients, it lowers it in others.
However, CBD effects have been shown to consistently reduce anxiety when present in higher concentrations in the cannabis plant. On its own, CBD has been shown in a number of animal and human studies to lessen anxiety. The stress-reducing effect appears to be related to activity in both the limbic and paralimbic brain areas.
A research review assessed a number of international studies and concluded that CBD has been shown to reduce anxiety , and in particular social anxiety, in multiple studies and called for more clinical trials. It is suggested that patients work with a health care practitioner experienced in recommending cannabidiol or medicinal cannabis so that dosage and delivery methods can be developed and fine-tuned on an individual basis. At the same time, educated and aware patients can be their own highly informed health consultants.
For anxiety, CBD products with a ratio of High-CBD cannabinoids can be very effective in reducing chronic anxiety, treating temporary stress, and protecting the body from the physiological effects of both.
Varieties high in linalool, a terpene shared with lavender, are known to be effective for relieving anxiety. Always start with the micro dose to test sensitivity and go up as needed within the dosing range, before going to the next, until symptoms subside. The micro to standard dose is usually recommended to treat stress and anxiety with CBD. For relief of immediate symptoms, as in a panic or anxiety attack, vaporizing or smoking work well.
The medication lasts one to three hours, whereas most ingested products, including CBD oil, take thirty to sixty minutes before taking effect and last six to eight hours. Herbal vaporizers that use the whole plant are also an effective delivery method.
Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products. The Cannabis Health Index CHI is an evidence-based scoring system for cannabis in general, not just CBD oil effects and its effectiveness on various health issues based on currently available research data.
Using this rubric and based on eleven studies, cannabis rated in the possible-to-probable range of efficacy for treatment of anxiety. Elixinol Organic High Potency CBD Capsules Elixinol offers a highly concentrated, high-potency, organic whole-hemp plant CBD oil , which is naturally extracted with carbon dioxide and free of all synthetics and chemicals. Whole-hemp plant extracts contain synergistic compounds that are believed to enhance the effectiveness and benefits of CBD. How the plant was used depended on the variety of cannabis, the parts of the plant, and how the plant was cultivated.
The variety of cannabis known as hemp was traditionally valued primarily for its fibers with high tensile strength, making it ideal for creating rope and textiles. Hemp seeds and sprouts were eaten as a good source of high-quality protein and beneficial omega-3 fatty acids.
The variety of cannabis known as marijuana was specifically cultivated for the euphoric properties of THC, which is concentrated mostly in the flower buds of the plant.
Only recently have the unique medicinal properties of both hemp and marijuana been fully recognized. Cannabis sativa has several alter egos, but marijuana and hemp are the two best known. Though both plants look the same, their chemical composition is quite different. The chemical difference has to do with the presence or absence of certain enzymes. Both marijuana and hemp contain a chemical substance called cannabigerol CBGA , which is concentrated mostly in the flower buds of the plant.
Remember, though, that there are many varieties of marijuana and hemp plants, and their concentrations of THC and CBD vary. Only cannabis with less than 0. There are different receptors for cannabinoid compounds located throughout the body. For instance, CB1 receptors are found in high concentrations in the brain and nervous system.
CB2 receptors are located throughout the body, but predominantly within the lower body and immune system. It weakly binds to both CB1 and CB2 receptors in the brain and body, gently stimulating and blocking them at the same time. This not only mildly activates the receptors, but is also thought to trigger the body to create more CB 1 and CB 2 receptors, a process known as upregulation.
It also results in increased natural levels of anandamide. When the body experiences an increase in CB receptors, it becomes more sensitive to the natural endocannabinoids anandamide and others already present in the body. CBD also modulates other receptors in the body. For instance, modulation of the 5-HT1A receptor involved with serotonin, a mood hormone provides mood-balancing properties: Another example is modulation of opioid receptors, which provides pain relief and tissue-supporting properties.
Cannabis plants also possess a wide spectrum of different chemical components offering a range of medicinal properties. Aside from cannabinoids, one of the most prominent chemicals in cannabis plants is terpenes, organic and aromatic compounds found in essential oils. Terpenes are beneficial on their own. For instance, research in the British Journal of Pharmacology found that terpenes are gastro-protective, suggesting they may be beneficial to people with ulcers, and that they have anti-inflammatory properties.
It also points to the importance of using a full-spectrum extract of hemp, which provides a full range of chemical components including terpenes, as opposed to purified CBD or CBD isolate, which contains only CBD. Cannabinoids, including cannabidiol CBD , work by mimicking natural endocannabinoids like anandamide described above in the body.
Endocannabinoids are part of a complex messaging system in the body called the endocannabinoid system. The endocannabinoid system oversees or regulates parts of the nervous system, endorphins, immune system functions, hormones, mood and emotions, metabolism, and many other chemical messengers in the body.
Like other cannabinoids, CBD readily crosses the blood brain barrier, making it ideal for affecting central nervous system conditions. CBD helps calm the nervous system, reduces inflammation, and is strongly neuroprotective. Not surprisingly, clinical studies evaluating cannabidiol for treatment of anxiety , post traumatic stress disorder PTSD , seizure disorders especially childhood seizures , and even schizophrenia have shown remarkable effectiveness.
Management of chronic pain is another application for which CBD is ideally suited, and it works in a number of ways. It and other non-THC cannabinoids found in hemp flower-bud extracts work to block pain-conducting nerve impulses, which reduces your perception of pain. Stimulation of CB 1 in the brain increases dopamine , which counteracts pain. Just as importantly, these same chemical substances reduce inflammation , the driving force behind pain , which allows healing to occur. CBD and other cannabinoids also reduce pain by affecting endorphins, the feel-good chemicals we naturally produce to suppress pain.
Unlike opioids heroin, narcotics , which mimic endorphins and ultimately suppress natural endorphins, cannabinoids modulate endorphins. This means, in effect, that CBD and cannabinoids increase natural endorphins.
So instead of causing dependence and addiction like opioids, CBD and cannabinoids do the opposite — so much so that CBD has proven valuable for countering narcotic and cocaine addiction. From a medicinal standpoint, the fact that CBD has the potential to relieve pain without causing euphoria, intoxication, or addiction makes it an intriguing therapeutic option — it has high potential for being at least a partial solution to the current opioid epidemic. CBD and other chemical substances in hemp flower-bud extracts are strong immune system modulators.
This means they control inflammation throughout the body, and also fine-tune the immune system for optimal performance. The wide range of benefits associated with cannabis have garnered interest for use in cancer therapy. Research suggests that cannabinoids, including CBD, may have anti-tumor effects. While this is not enough to define cannabis as a treatment for cancer, it does make it attractive as a complement to other therapies , for both reducing symptoms and possibly enhancing the effects of anticancer drugs.
Terpenes and the wide spectrum of other chemical compounds found in hemp flower-bud extracts provide potent anti-inflammatory and antioxidant properties.
This is a common source of confusion. Many people see hemp oil on grocery store shelves and assume or wonder if it contains CBD and other cannabinoids.
The hemp oil you might see on grocery store shelves is made by cold pressing hemp seeds. While hemp oil is a healthful option for a salad dressing, it has no medicinal value by itself. Cannabinoids, including CBD in hemp and THC in marijuana, are most highly concentrated in the flower buds, not the seeds.
These chemical components of the plant must be extracted from the flower buds to be useful. For medicinal use, cannabinoids are extracted from hemp and concentrated into a thick oil that, when ingested, elevates blood levels of cannabinoids for a more sustained period of time. CBD oil from hemp contains CBD and other cannabinoids, along with terpenes and other chemical components. The most common method, chemical extraction uses alcohol or hexane as solvents.
The solvent is dried off, leaving the dense oil — and possibly harmful residual solvents — behind. A newer method, CO 2 extraction is done without using chemical solvents. Instead, it uses carbon dioxide to extract the full range of chemical components from the flower buds and then distill them into dense CBD oil. Also sometimes called thermal extraction, vapor distillation uses hot air to safely vaporize the full spectrum of chemical components at high concentration from the buds, and then the vapor is distilled into CBD oil.
This method also activates the cannabinoids by removing an extra carboxyl ring from their molecular chain a chemical reaction called decarboxylation , enabling them to interact directly with CB receptors for maximal medicinal value.
I believe vapor distillation is the best method for obtaining the full range of activated chemical compounds from the cannabis plant. This method preserves the terpenes, which are beneficial on their own, and also enhance the properties of CBD via the entourage effect.
The upsides of lipid-based extraction are that the fat helps make the CBD more bioavailable easy to absorb , and there are no harsh solvents used. Condensed CBD oil can be taken as a thick paste, but this is the least pleasant option. More commonly, the CBD oil is mixed with a carrier oil, such as hemp oil or coconut oil, to a specific concentration of CBD.
The distinctive taste — which comes from the terpenes and not the cannabinoids — is often masked with chocolate, mint, or other flavorings. It typically comes in a small bottle with a dropper to administer the oil mixture. The best way to take CBD oil mixed with a carrier oil to a specific concentration is to place a few drops or dropperfuls under your tongue for 15 seconds to access the sublingual gland.
Early research has shown promising results for the use of CBD oil in relieving chronic pain. Many studies have found that CBD can reduce joint inflammation and other inflammatory pain in rats, without side effects. This may point to potential relief from arthritis in humans 3. In fact, one of the first trials of Sativex, a medicine that contains both CBD and THC, reported significant improvement in pain and sleep quality in 58 rheumatoid arthritis patients 4.
The same medicine showed a notable reduction in pain and muscle spasms in a small group of people with Multiple Sclerosis. Analyzing several trials and studies, a report concluded that adults treated with cannabis or cannabinoids, like CBD, are likely to experience a significant reduction in chronic pain symptoms 5. There is some indication that CBD oil could help treat anxiety and depression.
In various animal studies, CBD has shown notable anti-anxiety and antidepressant-like effects 6 , 7 , 8. With a group of 60 people, they found that CBD showed anti-anxiety effects, but only in specific doses. A case study on a child with post-traumatic stress disorder found that CBD oil helped safely reduce her anxiety and improve her sleep However, they did see some positive effects for those with social anxiety disorder There are some other dietary components thought to influence depression here.
While they emphasize that CBD is not a cure, plenty of research shows it can be highly beneficial in inhibiting the progression of many types of cancer, including breast, lung, prostate and colon cancer CBD is also effective in lowering cancer-related pain, as well as nausea and vomiting caused by chemotherapy.
Much of the research on CBD has looked at its seizure-reducing effects on two rare forms of childhood-onset epilepsy, Lennox-Gastaut syndrome and Dravet syndrome. In fact, the FDA just approved the first prescription cannabis drug, called Epidiolex, for these two forms of epilepsy Interestingly, CBD actually counteracts the psychoactive properties of THC, meaning it may help those addicted to marijuana. Some scientists also believe that CBD could have the potential to help treat type 2 diabetes and cardiovascular disease because of its anti-inflammatory properties.
It did appear to lower the incidence of diabetes in mice In fact, it may be more effective than vitamin C and E in improving skin conditions Early research has found that CBD oil has the potential to reduce chronic pain, anxiety, depression and acne, and may help those overcoming addiction.
Its anti-inflammatory properties may also play a role in lowering the risk of diabetes and cardiovascular disease. It has even shown anti-tumor effects and could be effective in inhibiting the progression of cancer and its related symptoms. CBD oil is generally safe, and even chronic use at high doses has shown to be well tolerated by humans There may also be potential interaction with other medicines.
6 Science-Backed CBD Oil Benefits (Plus: 4 Ways to Use It)
Cannabidiol, or CBD, is a chemical compound in marijuana with a variety of Here are seven health benefits of CBD oil that are backed by can be addictive and may lead to substance abuse (11). Sativex, an oral spray consisting of CBD and THC, has been proven to be a safe and effective way to. A person can use CBD oil in different ways to relieve various body weight, the concentration of the product, and the health issue. Cannabidiol (or CBD oil for short) is a unique compound that affects the for health, but it's important to understand how CBD oil differs.