A summary of historical treatment practices using cannabis for migraines Furthermore, these early clinical reports praise the apparent safety of long-term cannabis. Such trials are needed to determine short- and long-term efficacy for . Historical Reports of the Use of Cannabis as a Treatment for Headache (19th and Early. The effect of marijuana as a migraine treatment and prevention is still marking your record and creating long-term consequences in your life.
long of – a Cannabis treating headaches history
Each individual should consult with their doctor and the laws of the state they reside in before considering the possibility of using medical marijuana. Researchers have discovered that the human body has an endocannabinoid system ECS. The ECS is distributed throughout the body and plays a part in regulating many functions, including pain, mood, appetite, and the movement of the gastrointestinal system.
The ECS is comprised of the cannabinoids the body produces, the receptors on which they act, and the enzymes that are involved. While there are over a hundred different compounds called cannabinoids in cannabis, the two most commonly studied are THC deltatetrahydrocannabinol and CBD cannabidiol. CBD does not produce intoxicating effects, but it produces sedative effects that can help reduce pain, convulsions, nausea, and inflammation. Research on marijuana has been limited, due to the federal regulations and lack of funding.
However, there have been recent studies on the use of cannabis or medical marijuana in people with migraine. In , a retrospective analysis was published that reviewed data from adults with migraine who were recommended either a migraine preventive medicine or medical marijuana by their physician. The study found that the frequency of migraine attacks decreased from The types of marijuana used varied, and many patients used more than one form and used it daily as a prevention strategy.
Inhaled forms of marijuana were used most frequently as an acute strategy for migraine attacks and were reported to help ease migraine symptoms. It is impossible to know which form or dosage works best as a preventive or acute treatment, but the study provides interesting data to warrant further investigation. The researchers first studied the proper dose of cannabis. A group of 48 people with chronic migraine were given oral doses of medical marijuana with varying levels of THC and CBD.
In phase two of the research, 79 chronic migraine sufferers were given either a daily dose of marijuana or amitriptyline a common antidepressant used as a treatment for migraine. The participants were also able to use mg of marijuana for acute attacks. After three months, those who received marijuana had a Researchers also found that the medical marijuana used for acute treatment reduced pain intensity by The most common side effects were drowsiness and difficulty concentrating.
In addition, many participants noted an improvement in stomach aches and musculoskeletal pain. Marijuana is not approved by the U. Food and Drug Administration. Because marijuana is not tightly regulated the way approved drugs are, it is difficult to list side effects because its strength and purity may vary with each use.
The long-term negative effects of medical marijuana are not known. Few studies have been conducted on the long-term safety of cannabis, and those that have been completed are often conflicting or are of poor quality.
Fourteen people in the study reported experiencing side effects during treatment, such as sleepiness, bad dreams and nausea, the researchers said. There were more side effects associated with the use of edible marijuana than with its other forms.
The researchers said they don't know for sure why or how exactly marijuana may work to treat or prevent migraines. In fact, even the mechanisms of migraine as a condition are still not fully understood. In the study, the researchers were trying to evaluate the result of the treatment, even though they do not fully understand how it may work, Borgelt said.
However, there are several pathways that could explain why marijuana might work for patients with migraines, the researchers said. For example, some researchers have proposed that migraines might have something to do with a problem with receptors in the brain called cannabinoid receptors, which affect some crucial neurotransmitters such as serotonin. Compounds in marijuana may also affect these receptors, they said. It's also possible that serotonin itself plays a role in migraine headaches, Borgelt said, and some research has shown that THC, the ingredient in marijuana that's responsible for most of its psychological effects, may affect serotonin levels.
People with migraines should not try to self-medicate using marijuana, Borgelt stressed. Originally published on Live Science.
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Cannabis has a history as a headache remedy going back a few from ancient Greece and the Middle Ages of Europe also kept weed in their. to support the efficacy of cannabis for headache treatment, while . ceae, with botanical origin in Eastern or Central Asia (de Barge ;. Candolle ). Keywords: Migraine; Headache; Cannabis; Marijuana; Dronabinol; Ethnobotany. 1. Introduction Cannabaceae. Its botanical origin has been debated to be as.