Studies have shown cannabinoids effectively reduce the frequency and intensity of spasms, including in patients diagnosed with multiple sclerosis. Overview of. Cannabis has shown to be effective at reducing pain, muscle stiffness and spasms in multiple sclerosis patients5, In one study, multiple sclerosis patients saw. Recent studies have suggested that cannabinoid-based treatments may be beneficial in In particular, cannabidiol and the cannabinoic acids seem to be promising .. A practical overview of tizanidine use for spasticity secondary to multiple.
Research and Overview Spasms: Cannabinoids CBD
Muscle spasms will interfere with regular motor function and can cause distressing symptoms. If left untreated, spasms can lead to soft tissue shortening, which in turn can cause frozen or disabling contractures in the hip, knee, ankle, shoulder and elbow joints.
Along with pain, muscle spasm is the most common reason that cannabinoids is recommended and prescribed by medical professionals 2. Studies have demonstrated that cannabinoids offers significant improvements in muscle spasticity, both in mice trials and in human subjects 1,2. THC and CBD have demonstrated that they interact with the CB 1 and CB 2 receptors and their actions on the two receptors regulates the excitatory and inhibitory neurotransmitters necessary to curtail spasms 6,8.
For those whose spasms and spasms are related to multiple sclerosis, cannabis has demonstrated it can offer relief 9. In what was the largest multinational clinical trial of its kind, multiple sclerosis patients suffering from spasms were treated with cannabis containing THC and CBD. After 12 weeks, the patients experienced significantly reduced spasticity severity compared with patients receiving the placebo.
While the trial lasted 12 weeks, patients reported significant improvements in spasticity after just four weeks 8. The same patients also reported significant improvement in quality-of-life measures over the 16 weeks In another study, approximately two-thirds of patients reported improvements in spasticity after 50 weeks of treatment with cannabis containing THC and CBD 4. Cannabis has even shown to be effectively lower the frequency and intensity of spasms in multiple sclerosis patients whose spasms had been previously unrelieved by traditional anti-spasticity therapy.
After 15 weeks of treatment, patients saw a significant reduction in spasticity. Improvements were seen within the first four weeks 3. Currently, 17 states have approved medical cannabis for the treatment of spasms. A number of other states will consider allowing medical cannabis to be used for the treatment of spasms not related to multiple sclerosis with recommendation by a physician. Spasms that had previously proven to be untreatable by traditional efforts were significantly reduced after four weeks of cannabis treatment.
A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis. Your email address will not be published. Federal Tax ID The information contained in this website is for general information and educational purposes only. It does not constitute medical advice. Therefore, any reliance you place on such information is strictly at your own risk.
Please check with your medical doctor before starting or changing your CBD routine. I accept the terms and conditions and am aware that this notification will not appear again during an unspecified time. Overview of Spasms Spasms are when your muscles are stiff and experience involuntary contractions.
Today, I want to discuss something related, but more accessible, to medical marijuana that has made a major impact on my life: CBD cannabidiol derived from Hemp. As I explained in my medical marijuana article, the compounds that are most helpful for our symptoms are called cannabinoids.
Cannabinoids mimic naturally occurring compounds in our body called endocannabinoids. The most basic description of how all this works is that these compounds can change and improve the way our cells communicate with each other. When we take in cannabinoids, they interact with the already existing endocannabinoid system of our bodies and the cannabinoid receptors found in all human cells.
THC is the compound associated with the more psychoactive effects of marijuana. These effects can be very helpful to those with MS, however, they are also the reason marijuana is constantly fighting a legal battle. Here is where hemp comes in! Because of this, it is much easier to obtain CBD oil produced from hemp than from the cannabis plant.
This sounds great, right? Producing and selling CBD oil has become a big business, but it can be extremely hard to find consistent and effective product. There are various extraction methods for getting CBD oil from the hemp plant, some more effective than others, and you rarely know which method a company has used.
That can making finding a consistent and effective CBD product difficult. I was still very skeptical, more so than I was with medical marijuana. I then began using this tincture each day by placing a few drops under my tongue. I found that the key for me was doing this every day regardless of how bad my symptoms were.
Consistency has been the important factor to me. When I take it every day, or even close to every day, my body is much better off. Less pain, less spasticity, and less fatigue. Hard to believe, even for me. I stress that consistency and quality are important aspects of CBD usage for me. Quality CBD products can be expensive, though in my experience, less expensive than medical marijuana and much more easily obtainable you do not need a special medical marijuana card or prescription.
If you have the means and desire, go ahead and try it. As always, do some research on your own as well, there is a wealth of resources and groups related to CBD use for chronic illness. Good news - you're already subscribed! Let us know at contact MultipleSclerosis. Try again or let us know at contact MultipleSclerosis. How long did it take you to figure out the best dosage and how long after starting CBD oil did you notice a difference?
Hi Lucylucylucy, it took me a while of consistent use, a few months really. I also had friends tell me they noticed a change before I even really noticed myself. It was all so slow and incremental. Hi Devin, That makes sense. I am an impatient sort so I will try to keep my expectations under control. Thanks for your response.: Thank you TerryLSwindle, I currently use Lazarus Naturals, but I encourage everyone to experiment and find one that works well for you.
You can find a good list of companies that are independently tested here: The top reason for this, is poor bioavailability of drug molecules or the supplement is not water soluble. So a person needs to consume 10 times the therapeutic recommended dose to get any therapeutic effect. You need far less to get the milligrams that are recommended and receive the desired result. This product will server you very well and results, immediately. Devin, almost as if I somehow sensed would be needing it even more a year later, my wife and I began using HempMeds products the RSHO line a year ago for other things.
Which one of their products are you finding to be the most helpful for you? And while everyone will respond differently, would you be willing to share how much you found to be your optimum intake and how often? I wanted the higher concentration but have been using less. I also like that Lazurus Naturals has all of their batches tested by a third party and you can even download the results of those tests.
I still utilize Tysabri as my primary means of fighting the disease. However, CBD oil has been extremely help for issues like spasms and pain. There is a fantastic online CBD community at: Hi Devin, I have MS nearly 20 years now, and surviving. As I am taking it for the first time I do not know what to expect.
How fast do you know will I start feeling something? It is 2 weeks now, and I do not feel anything. Not relaxed, not more tired than usual, nor sleeping better or worse just the same. From Your posts I see you have some experience. Please if you have any comments or information you can share with me I would appreciate very much. Thanks in advance and have a nice weekend Nicole. Hi Devin, I love your writing. Very real and down to earth thank you so much. I was dx rrms mid dx spms. I used a wheelchair fulltime over 7 yrs.
Had went off DMT Started making and taking RSO oil. Cannabis oil in about 8 months I was walking! With help to start with. Within a year walked and drove on my own for over 3 years feeling better than the last 20yrs.
Dr had me stop RSO oil before surgery.
Spasms: Cannabinoids and CBD Research Overview
The cannabis plant contains many biologically active chemicals, including The review of original studies by Bergamaschi et al. Cannabidiol Reduces Spasticity, Pain, Inflammation, Fatigue, and Depression in PwMS. While several studies have shown the potential of cannabinoids to treat some Theoretically, CBD holds greater therapeutic potential than THC, since THC improved spasticity-related symptoms and pain in patients with MS. In summary, cannabis-derived compounds hold potential to treat MS and “to. Quality and consistency are key when using CBD (cannabidiol) derived from hemp to manage MS pain, spasticity, and fatigue. When we take in cannabinoids, they interact with the already existing I'm most certainly not an expert on all things CBD, but I did do some research and found a place online.